Condition: Insulin Resistance · NAFLD · Sponsor: Yale University
The purpose of this study is to examine whether weight reduction decreases intramyocellular (IMCL) and hepatic lipid content, and improves insulin sensitivity of muscle and fat tissue in people who are insulin resistant and have a family history of type 2 diabetes. Hepatic mitochondrial oxidation will be assesses using a 3 hour triple tracer study (D7 glucose, 3-13C lactate and 13C4 beta-hydroxybutyrate).
This description comes directly from the study's public registry record.
Kitt Petersen, MD · 203-785-5447 · kitt.petersen@yale.edu
Always discuss trial participation with your own doctor first.
| Magnetic Resonance Research Center (MRRC) | New Haven, Connecticut, United States | Enrolling By Invitation |
| Yale Center for Clinical Investigation HRU | New Haven, Connecticut, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT02193295