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Study identifier: NCT02161783 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Treatment of Graft Failure After Hematopoietic Stem Cell Transplantation

Condition: Primary Graft Failure · Secondary Graft Failure  ·  Sponsor: Masonic Cancer Center, University of Minnesota

PhaseN/A
Planned participants50
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This is a guideline for the treatment of graft failure after hematopoietic stem cell transplant (HSCT). This regimen, consisting of cyclophosphamide and fludarabine with low dose total body irradiation (TBI) is designed to promote donor engraftment by day 42 after initial graft failure. The graft will consist of bone marrow or G-CSF mobilized peripheral blood from a haploidentical related donor. The source of stem cells will be determined by the transplant team based on factors such as patient's age, medical history, donor availability and will be according to the current University of Minnesota Blood and Marrow Transplantation Program selection guidelines.

This description comes directly from the study's public registry record.

Talk to the study team

Timothy Krepski  ·  612-273-2800  ·  tkrepsk1@fairview.org

Always discuss trial participation with your own doctor first.

Locations (1)

University of Minnesota Medical Center, FairviewMinneapolis, Minnesota, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02161783