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Study identifier: NCT02115295 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia

Condition: Acute Biphenotypic Leukemia · Acute Myeloid Leukemia · Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive  ·  Sponsor: M.D. Anderson Cancer Center

PhasePhase 2
Planned participants508
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This phase II trial studies how well cladribine, idarubicin, cytarabine, and venetoclax work in patients with acute myeloid leukemia, high-risk myelodysplastic syndrome, or blastic phase chronic myeloid leukemia. Drugs used in chemotherapy, such as cladribine, idarubicin, cytarabine, and venetoclax, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

This description comes directly from the study's public registry record.

Talk to the study team

Tapan Kadia  ·  713-792-7305  ·  tkadia@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT02115295