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Study identifier: NCT01926587 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine

Condition: Myelodysplastic Syndrome · Acute Myeloid Leukemia · Chronic Myelomonocytic Leukemia  ·  Sponsor: Traws Pharma, Inc.

PhasePhase 1/Phase 2
Planned participants45
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study, is a Phase I/II clinical trial in three parts: Phase I Dose Escalation, Phase II, Part 1 RPTD Cohort, and Phase II, Part 2 Expansion. The first two parts have been completed. The Phase II, Part 2 Expansion will assess if treatment with rigosertib in combination with azacitidine, has measurable effects in patients with myelodysplastic syndrome (MDS). Safety of patients is an objective throughout all parts of the study.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (13)

Banner MD Anderson Cancer CenterGilbert, Arizona, United States
City of HopeDuarte, California, United States
Desert Hematology Oncology Medical Group, Inc.Rancho Mirage, California, United States
Rush University Medical CenterChicago, Illinois, United States
Cancer Center of KansasWichita, Kansas, United States
Saint Louis UniversitySt Louis, Missouri, United States
Roswell Park Cancer InstituteBuffalo, New York, United States
Mount Sinai Medical CenterNew York, New York, United States
White Plains Hospital Center for Cancer CareWhite Plains, New York, United States
Carolina Blood and Cancer Care AssociatesRock Hill, South Carolina, United States
The University of Texas MD Anderson Cancer CenterHouston, Texas, United States
Froedtert Hospital and the Medical College of WisconsinMilwaukee, Wisconsin, United States

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT01926587