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Study identifier: NCT01898039 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Modified Vaccine for High Risk or Low Residual Melanoma Patients

Condition: Malignant Melanoma  ·  Sponsor: Hadassah Medical Organization

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This study is designed for patients who had malignant melanoma and, following tumor removal, are now free of disease, or have only very minor residual disease, and are at a very high risk of disease recurrence. These patients will be treated with the A2/4-1BBL melanoma vaccine, a compatible melanoma cell line that has been engineered to express a molecule termed 4-1BBL, which enhances the chances of the cell line to be recognized by the patient's immune system, and to induce its stimulation. The hypothesis that drives the study states that the immune response against the cell line will also be effective against the residual tumor that may still be present in the body.

This description comes directly from the study's public registry record.

Talk to the study team

Hani Steinberg, RN  ·  972507874292  ·  hanis@hadassah.org.il

Always discuss trial participation with your own doctor first.

Locations (1)

Sharett Institute of Oncology, Hadassah Medical OrganizationJerusalem, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT01898039