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Study identifier: NCT01891318 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Condition: Tumors Metastatic to Brain  ·  Sponsor: Case Comprehensive Cancer Center

PhasePhase 1/Phase 2
Planned participants36
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase I/II trial studies the ability to stop brain metastases from coming back after treatment with radiosurgery followed by surgical resection. It will also evaluate the side effects of these combined treatments and help determine the best radiosurgery dose. Radiosurgery focuses the x-rays directly to the tumor and cause less damage to the normal tissue in the brain.

This description comes directly from the study's public registry record.

Talk to the study team

Erin Murphy, MD  ·  1-866-223-8100  ·  TaussigResearch@ccf.org

Always discuss trial participation with your own doctor first.

Locations (2)

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesWithdrawn
Cleveland Clinic, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT01891318