Condition: Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive · Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia · Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive · Sponsor: M.D. Anderson Cancer Center
This phase II trial studies how well ponatinib hydrochloride works as second line therapy in treating patients with chronic myeloid leukemia in chronic phase that has not responded to initial treatment (first line) with imatinib mesylate, dasatinib, or nilotinib or cannot tolerate imatinib mesylate, dasatinib, or nilotinib. Ponatinib hydrochloride may stop or control the growth of cancer cells by blocking a protein needed for cell growth.
This description comes directly from the study's public registry record.
Elias Jabbour, MD · (713) 792-4764 · ejabbour@mdanderson.org
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| M D Anderson Cancer Center | Houston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT01746836