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Study identifier: NCT01731444 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phenylephrine Tumescence for Hemostasis in Surgery for Burn Injury

Condition: Blood Loss, Surgical  ·  Sponsor: University of Manitoba

PhasePhase 1
Planned participants24
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The standard of care for treatment of burn injury is to inject a solution of epinephrine under the skin of the injured site in order to reduce blood loss during skin grafting. This solution of epinephrine has been shown to have effects on the body outside the donor site. Some people have increases in heart rate and blood pressure. We will study the effect of a phenylephrine solution in place of an epinephrine solution to control blood loss. We think that phenylephrine will help decrease blood loss and not change blood pressure or heart rate. The injured area will be injected under the skin and a skin graft will be taken in the same way as we usually do. The only change will be the use of phenylephrine in the solution instead of epinephrine. Our goal is to find whether or not phenylephrine or epinephrine solution results in a reduction of blood loss without affecting the rest of the body.

This description comes directly from the study's public registry record.

Talk to the study team

Justin Gawaziuk, MSc  ·  2047873669  ·  jgawaziuk@hsc.mb.ca

Always discuss trial participation with your own doctor first.

Locations (1)

University of ManitobaWinnipeg, Manitoba, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT01731444