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Study identifier: NCT01627301 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sympathetic Overactivity in Post-traumatic Stress Disorder

Condition: Post-traumatic Stress Disorder · Prehypertension  ·  Sponsor: Emory University

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This study will evaluate whether 8 weeks of daily DGB therapy or transcutaneous vagus nerve stimulation (tVNS) therapy improves SNS activity at rest and during stress.

This description comes directly from the study's public registry record.

Talk to the study team

Deirdre Dixon, MS  ·  404-321-6111  ·  deirdre.dixon@emory.edu

Jeanie Park, MD  ·  404-321-6111

Always discuss trial participation with your own doctor first.

Locations (1)

Atlanta VA Medical CenterDecatur, Georgia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT01627301