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Study identifier: NCT01273129 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Surgery as a Treatment for Medically Intractable Epilepsy

Condition: Epilepsy · Epilepsy, Temporal Lobe · Partial Epilepsy  ·  Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

PhaseN/A
Planned participants300
Who can joinAll sexes, 8 Years to 99 Years
Healthy volunteersNo

About this study

Background: \- Drug resistant epilepsy is the term used to describe epilepsy that cannot be controlled by medication. Many people whose seizures do not respond to medication will respond to surgical treatment, relieving seizures completely or almost completely in one-half to two-thirds of patients who qualify for surgery. The tests and surgery performed as part of this treatment are not experimental, but researchers are interested in using the data collected as part of routine standard epilepsy care to better understand epilepsy and its treatment. Objectives: \- To use surgery as a treatment for drug resistant epilepsy in children and adults. Eligibility: \- Children and adults at least 8 years of age who have simple or complex partial seizures (seizures that come from one area of the brain) that have not responded to medication, and who are willing to have brain surgery to treat their medically intractable epilepsy. Design: * Participants will be screened with a medical history, physical examination, and neurological examination. Imaging studies, including magnetic resonance imaging and computer-assisted tomography (CT), may also be conducted as part of the screening. Participants who do not need surgery or whose epilepsy cannot be treated surgically will follow up with a primary care physician or neurologist and will not need to return to the National Institutes of Health for this study. * Prior to the surgery, participants will have the following procedures to provi…

This description comes directly from the study's public registry record.

Talk to the study team

Gretchen C Scott, R.N.  ·  Not Listed  ·  SNBrecruiting@nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT01273129