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Study identifier: NCT01193075 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Condition: Charcot Marie Tooth Disease  ·  Sponsor: Michael Shy

PhaseN/A
Planned participants5000
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersYes

About this study

This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C). The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window

This description comes directly from the study's public registry record.

Talk to the study team

Nicole M Kressin, MSN, RN  ·  319-384-6362  ·  UICMTClinic@uiowa.edu

Tiffany Grider, MS, CGC  ·  319-384-6362  ·  UICMTClinic@uiowa.edu

Always discuss trial participation with your own doctor first.

Locations (22)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
University of Colorado HospitalAurora, Colorado, United StatesRecruiting
University of Connecticut/Connecticut Children's Medical CenterHartford, Connecticut, United StatesRecruiting
Children's National HospitalWashington D.C., District of Columbia, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Nemours Children's HealthOrlando, Florida, United StatesRecruiting
Nemours Children's HospitalOrlando, Florida, United StatesRecruiting
University of IowaIowa City, Iowa, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Harvard/Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesNot Yet Recruiting

+ 10 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT01193075