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Study identifier: NCT01143480 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

Condition: Asthma · Atherosclerosis · Metabolic Syndrome  ·  Sponsor: National Institute of Environmental Health Sciences (NIEHS)

PhaseN/A
Planned participants725
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersYes

About this study

Background: \- Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body s response can contribute to chronic illnesses or diseases such as asthma and certain types of cancers. Objectives: \- To examine how specific genes and proteins in blood cells respond to environmental exposures. Eligibility: \- Healthy volunteers between 18 and 45 years of age. Design: * The study will involve one visit of 45 to 60 minutes. * Participants will be screened with a brief physical examination and finger stick to determine if they are eligible to donate blood for the study, and will complete a questionnaire about any medications or other drugs (e.g., cigarettes) they may be taking. * Participants will provide a blood sample for research purposes.

This description comes directly from the study's public registry record.

Talk to the study team

NIEHS Join A Study Recruitment Group  ·  (855) 696-4347  ·  myniehs@nih.gov

Michael B Fessler, M.D.  ·  (984) 287-4081  ·  fesslerm@niehs.nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

NIEHS Clinical Research Unit (CRU)Research Triangle Park, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT01143480