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Study identifier: NCT01143454 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Condition: Metabolic Disease · Obesity · Li-Fraumeni Syndrome  ·  Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

PhaseN/A
Planned participants5000
Who can joinAll sexes, 1 Year to 100 Years
Healthy volunteersYes

About this study

Background: \- Researchers are interested in studying individuals who have known or suspected metabolic, inflammatory or genetic diseases that may put them at a high risk for heart diseases or diseases of their blood vessels. Depending on the condition being studied, both affected and nonaffected individuals may be asked to provide blood and other samples and may undergo tests to evaluate the heart, blood vessels and lung function. The testing is tailored to the individual and/or condition being studied. Nonaffected individuals may include relatives of affected individuals and healthy nonrelated volunteers. Objectives: \- To study individuals who have or are at risk for cardiovascular diseases, and in some cases their unaffected relatives and healthy volunteers. Eligibility: \- Individuals between 1 and 100 years of age. Participants may be healthy volunteers, individuals with cardiovascular diseases, or unaffected relatives of individuals with cardiovascular diseases. Design: * Participants will have some or all of the following tests, as directed by the study researchers: * Photography of the face and full body * Body measurements * Radiography, including chest or limb x-rays * Metabolic stress testing to study heart and muscle function * Echocardiography to study heart function * Magnetic resonance imaging (MRI) studies, including cardiovascular MRI, angiography, and contrast MRI, to study heart function and performance * Computed tomography (CT) angiogram to obtain…

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca D Huffstutler, C.R.N.P.  ·  (301) 594-1281  ·  rebecca.huffstutler@nih.gov

Always discuss trial participation with your own doctor first.

Locations (3)

Hope CenterWashington D.C., District of Columbia, United StatesRecruiting
Suburban HospitalBethesda, Maryland, United StatesCompleted
National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT01143454