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Study identifier: NCT00929006 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism

Condition: Puberty · Hyperandrogenism  ·  Sponsor: University of Virginia

PhaseEARLY_Phase 1
Planned participants36
Who can joinFemale, 10 Years to 17 Years
Healthy volunteersYes

About this study

The purpose of this study is two-fold. (1) We will determine if in mid- to late pubertal girls without hyperandrogenism (HA), progesterone (P4) acutely reduces waking luteinizing hormone (LH) frequency to a greater extent than sleep-associated LH frequency. (2) We will determine if in mid- to late pubertal girls with HA, P4 will acutely suppress waking LH frequency to a lesser degree than it does in girls without HA.

This description comes directly from the study's public registry record.

Talk to the study team

Melissa Gilrain  ·  434-243-6911  ·  pcos@virginia.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of VirginiaCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT00929006