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Study identifier: NCT00756769 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Systemic Lupus Erythematosus in Gullah Health

Condition: Systemic Lupus Erythematosus  ·  Sponsor: Medical University of South Carolina

PhaseN/A
Planned participants750
Who can joinAll sexes, 2 Years to no upper limit
Healthy volunteersYes

About this study

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies, multiple organ involvement, and diverse clinical symptoms and immunologic manifestations. African Americans are at a disproportionately higher risk of developing SLE, develop SLE at an earlier age, and have increased morbidity and mortality compared with European Americans. Our central study hypothesis is that there are specific genetic factors that interact with environmental exposures leading to the development of SLE. The African American Gullah population from the Sea Islands of South Carolina and Georgia are unique in their genetic homogeneity with minimal non-African genetic admixture, making them an ideal cohort to address questions of environmental and genetic influence on the development and progression of SLE.

This description comes directly from the study's public registry record.

Talk to the study team

Diane L. Kamen, MD, MSCR  ·  843-792-4825  ·  kamend@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT00756769