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Study identifier: NCT00397280 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Immune Cell Response to Stimuli

Condition: Inflammation  ·  Sponsor: National Institute of Environmental Health Sciences (NIEHS)

PhaseN/A
Planned participants750
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This study will investigate the response of immune cells (neutrophils, monocytes) to various signals in the test tube to determine how they sense the signals in the body and what substances they produce in response to them. It will determine how the cells may, under certain circumstances, contribute to inflammation, and will measure substances in the blood plasma (the liquid, non-cellular part of the blood) that might stimulate white blood cells, in order to understand how the blood responds to possible disease-related conditions. Healthy normal volunteers 18 years of age and older who weigh at least 110 pounds may be eligible for this study. Participants give about 320 milliliters (mL) of blood (about 1 1/3 cups) or less at each donation. They donate no more than once every 8 weeks and no more than six times a year. On some occasions, less than 320 mL of blood may be drawn. The collected blood is separated into its components and specific cells are exposed to substances to examine their response.

This description comes directly from the study's public registry record.

Talk to the study team

NIEHS Join A Study Recruitment Group  ·  (855) 696-4347  ·  myniehs@nih.gov

Michael B Fessler, M.D.  ·  (984) 287-4081  ·  fesslerm@niehs.nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

NIEHS Clinical Research Unit (CRU)Research Triangle Park, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT00397280