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Study identifier: NCT00237315 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Longitudinal Study of Urea Cycle Disorders

Condition: Brain Diseases, Metabolic, Inborn · Amino Acid Metabolism, Inborn Errors · Urea Cycle Disorders  ·  Sponsor: Andrea Gropman

PhaseN/A
Planned participants1500
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Urea cycle disorders (UCD) are a group of rare inherited metabolism disorders. Infants and children with UCD commonly experience episodes of vomiting, lethargy, and coma. The purpose of this study is to perform a long-term analysis of a large group of individuals with various UCDs. The study will focus on the natural history, disease progression, treatment, and outcome of individuals with UCD.

This description comes directly from the study's public registry record.

Talk to the study team

Jennifer Seminara, MPH  ·  202-306-6489  ·  jseminar@childrensnational.org

Always discuss trial participation with your own doctor first.

Locations (15)

University of California, Los AngelesLos Angeles, California, United StatesRecruiting
Stanford University Medical CenterStanford, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
Children's National Medical CenterWashington D.C., District of Columbia, United StatesRecruiting
Children's Hospital Boston (UCDC New England Center)Boston, Massachusetts, United StatesRecruiting
University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting
Case Western Medical CollegeCleveland, Ohio, United StatesRecruiting
Oregon Health and Science UniversityPortland, Oregon, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting
Children's Hospital and Regional Medical CenterSeattle, Washington, United StatesRecruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT00237315