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Study identifier: NCT00001238 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders

Condition: Kidney Cancer · Urologic Malignant Disorders · Renal Cell Carcinoma  ·  Sponsor: National Cancer Institute (NCI)

PhaseN/A
Planned participants5000
Who can joinAll sexes, 2 Years to no upper limit
Healthy volunteersYes

About this study

We will investigate the clinical manifestations and molecular genetic defects of heritable urologic malignant disorders. Families with urologic malignancy with known or suspected genetic basis will be enrolled. Affected individuals or individuals suspected of having a germline urologic malignant disorder will undergo periodic clinical assessment and genetic analyses for the purpose of: 1) definition and characterization of phenotype, 2) determination of the natural history of the disorder, and 3) genotype/phenotype correlation. Genetic linkage studies may be performed in situations in which the genetic basis of the disorder has not been elucidated.

This description comes directly from the study's public registry record.

Talk to the study team

Deborah A Nielsen, R.N.  ·  (240) 760-6247  ·  deborah.nielsen@nih.gov

W. Marston Linehan, M.D.  ·  (240) 858-3700  ·  linehanm@mail.nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT00001238